We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Read More
8
Zinc reduces cold duration
Zinc Supplementation Reduces Common Cold Duration among Healthy Adults: A Systematic Review of Randomized Controlled Trials with Micronutrients Supplementation.
We explored the impact of zinc supplementation on common cold symptoms through an extensive review of 20 randomized controlled trials. These studies focused on observing how micronutrients, especially zinc, can help manage the cold in healthy adults.
Our findings suggest that while zinc did not significantly prevent the incidence of cold or reduce symptom severity when compared to other micronutrients, it showed promising results in potentially shortening the duration of a cold. Specifically, we observed that zinc could cut down the duration of cold symptoms by approximately 2.25 days when used alone.
This reduction in duration could have a meaningful impact on daily life and overall productivity for those affected by the common cold. It's noteworthy that while zinc proves beneficial, other vitamins like vitamin C and vitamin D did not show the same effectiveness in this context.
Read More
4
Zinc may shorten cold duration
Zinc for prevention and treatment of the common cold.
We explored how zinc supplementation might impact the prevention and treatment of the common cold. Through a thorough examination of 34 studies involving over 8,500 participants, we aimed to understand whether zinc could effectively reduce the occurrence or duration of colds.
The studies included randomized controlled trials comparing zinc to placebo in both children and adults. Our findings indicate that while zinc may not significantly lower the risk of catching a cold, it could help reduce the duration of an ongoing cold. However, this benefit comes alongside an increase in non-serious side effects, such as an unpleasant taste and stomach issues.
It's important to note that many of these studies showed a wide range of interventions and outcomes, and some reporting was incomplete. Overall, our results suggest that zinc does not hold substantial promise for preventing colds, but it may help shorten the duration of symptoms once a cold strikes.
Read More
Most Useful Reviews
9
Increased strength
256 people found this helpful
I am grateful to iHerb for their fast delivery and reliable packaging. Solgar's vitamins have truly strengthened my health; I previously suffered frequent colds and weakness. Since taking these vitamins, my complexion is healthy, and I handle colds better.
Read More
10
Covid recovery
102 people found this helpful
This zinc picolinate has been vital for my immunity. It proved effective during my mild Covid-19 bout. The small, smooth tablets are easy to swallow and have no unpleasant taste. I recommend it for anyone needing good immunity support.
Read More
9
Reduced hair loss
61 people found this helpful
After suffering from hair loss and other health issues, I discovered a significant zinc deficiency. Taking zinc picolinate has resolved my hair loss, stabilised my vision, and enhanced my resilience to common colds. I am very satisfied with this product.
We explored the effectiveness of zinc in combination with herbal polyphenols against respiratory RNA viruses, including the common cold. In this study, the researchers combined zinc picolinate with various flavonoids to see if it could reduce viral replication and load without harming healthy cells.
The results were quite promising, showing a significant reduction of 50-95% in the genome replication levels of viruses like the human coronavirus OC43, influenza A virus, and human metapneumovirus. This suggests that zinc, when paired with appropriate compounds, may play a beneficial role in treating infections that lead to the common cold.
However, it's important to note that while the study shows a notable decrease in viral activity, it did not specifically isolate the effects of zinc alone. Thus, we cannot definitively state that zinc by itself is effective against the common cold without considering the contributions of the other substances involved.
Overall, this research opens the door for developing a potential treatment that is not toxic and sourced from natural ingredients, which could be effective against various RNA viruses with the hope of remaining effective even amidst mutating strains.
Read More
9
Zinc shortens cold duration variability
Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration.
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Read More
8
Zinc reduces cold duration
Zinc Supplementation Reduces Common Cold Duration among Healthy Adults: A Systematic Review of Randomized Controlled Trials with Micronutrients Supplementation.
We explored the impact of zinc supplementation on common cold symptoms through an extensive review of 20 randomized controlled trials. These studies focused on observing how micronutrients, especially zinc, can help manage the cold in healthy adults.
Our findings suggest that while zinc did not significantly prevent the incidence of cold or reduce symptom severity when compared to other micronutrients, it showed promising results in potentially shortening the duration of a cold. Specifically, we observed that zinc could cut down the duration of cold symptoms by approximately 2.25 days when used alone.
This reduction in duration could have a meaningful impact on daily life and overall productivity for those affected by the common cold. It's noteworthy that while zinc proves beneficial, other vitamins like vitamin C and vitamin D did not show the same effectiveness in this context.
Read More
7
Zinc's unclear role in colds
Potential Role of Vitamins and Zinc on Acute Respiratory Infections Including Covid-19.
We explored the potential effects of zinc on the common cold based on a collection of research studies that investigated its role in treating acute respiratory infections, including COVID-19.
Importantly, we found that while zinc showed some promise in improving conditions related to pneumonia in children under five, there wasn't enough clear evidence linking zinc directly to a reduction in the incidence or duration of the common cold.
Typically, vitamins C, D, and E were examined alongside zinc, with findings indicating that these vitamins did not lower the common cold's occurrence. However, we noted that vitamin C did help shorten its duration and lessen its severity for some individuals, particularly those under physical or environmental stress.
Ultimately, while zinc has been shown to support health in various contexts, its specific impact on the common cold remains uncertain, suggesting that additional research is needed to draw more definitive conclusions.
We observed that zinc has been highlighted as a potential remedy for alleviating symptoms of the common cold. The information indicates that zinc may play a significant role in treating cold symptoms, especially in adults. While conclusive and thorough evidence specifically isolating zinc's effects isn't entirely clear, it is often included among over-the-counter treatments that have shown effectiveness.
Zinc is typically administered to support quicker recovery from cold symptoms, which also include nasal congestion and sore throat. It’s essential that we keep in mind that not all evidence is of high quality, but some studies and anecdotal reports suggest that incorporating zinc may lead to some improvement in symptom management.
Furthermore, it's important to emphasize that when advising patients, we should be mindful of the limitations and mix of other treatments. Although zinc appears promising, it's crucial to inform individuals that effective treatment strategies extend beyond just zinc alone. While the potential benefits of zinc are appealing, more reliable research is necessary to fully endorse its effectiveness in cold treatment.
I am grateful to iHerb for their fast delivery and reliable packaging. Solgar's vitamins have truly strengthened my health; I previously suffered frequent colds and weakness. Since taking these vitamins, my complexion is healthy, and I handle colds better.
Read More
10
Covid recovery
102 people found this helpful
This zinc picolinate has been vital for my immunity. It proved effective during my mild Covid-19 bout. The small, smooth tablets are easy to swallow and have no unpleasant taste. I recommend it for anyone needing good immunity support.
Read More
9
Reduced hair loss
61 people found this helpful
After suffering from hair loss and other health issues, I discovered a significant zinc deficiency. Taking zinc picolinate has resolved my hair loss, stabilised my vision, and enhanced my resilience to common colds. I am very satisfied with this product.
Read More
9
Supports immune health
25 people found this helpful
Zinc is essential for our health, especially for the immune system. It helps absorb vitamin A and fights hormonal disorders. The best compounds are picolinate and citrate. Since taking zinc picolinate during cold season, my family has remained healthy. However, it's crucial not to abuse it and maintain recommended doses.
Read More
10
Boosts immunity
22 people found this helpful
Zinc is vital for our immune defence. With its deficiency, vulnerability to viruses increases. This form of zinc improves skin health and aids testosterone metabolism. I have personally found it effective and recommend it for overall health.
The common cold is a viral infection of the upper respiratory tract, primarily affecting the nose and throat. It's caused by a variety of viruses, with rhinoviruses being the most prevalent. Symptoms generally include a runny or stuffy nose, sore throat, cough, sneezing, mild headache, and sometimes a low-grade fever. While the common cold is often mild and resolves on its own within a week or two, it can still be bothersome and impact daily activities.
Transmission occurs through respiratory droplets when an infected person coughs or sneezes, or by touching surfaces contaminated with the virus. Preventative measures include frequent handwashing, using hand sanitizer, and avoiding close contact with infected individuals. Since there is currently no cure for the common cold, treatment focuses on symptom relief through over-the-counter medications, adequate rest, and hydration. While colds may be uncomfortable, they are generally not serious; however, seeking medical attention may be necessary if symptoms worsen or persist for an extended period.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential benefits in reducing the duration and severity of the common cold. Several clinical trials suggest that taking zinc supplements may help shorten colds by up to one day when taken within the first 24 hours of symptom onset. Zinc may work by inhibiting the replication of rhinoviruses, which are common causes of the cold, and by modulating immune responses.
However, it's important to note that the evidence is mixed. Not all studies agree on zinc’s effectiveness, and some show minimal benefits. Additionally, taking zinc in excessive amounts can lead to adverse side effects, including nausea and a bad taste in the mouth. For those considering zinc supplements, it's advisable to consult with a healthcare provider to determine appropriate dosages and to discuss any potential interactions with existing medications. Overall, while zinc may offer some relief for colds, it's best used as a part of a broader strategy that includes good hygiene, plenty of rest, and adequate hydration.
Based on user reviews, individuals report experiencing varying timelines for relief from common cold symptoms when taking zinc supplements, specifically zinc picolinate. Many users suggest that if taken at the initial signs of a cold, noticeable improvements can occur within as little as one to two days. For instance, one user mentioned that symptoms notably diminished after just a day or two of taking zinc twice daily Read Review. Another review emphasizes the importance of starting zinc as soon as cold symptoms arise for it to be most effective Read Review.
Other users have reported longer-term benefits, including a significant boost in overall immunity, which may translate to decreased frequency of colds over time. One user highlighted that they hadn't experienced any colds within a five-month period while taking the supplement daily Read Review. Overall, while some seek immediate relief through zinc, others use it as a preventative measure during cold season, indicating its potential efficacy both during acute illness and for long-term immune support.
Zinc supplementation has garnered attention for its potential to alleviate the common cold, primarily by reducing the duration of symptoms rather than preventing the onset. Research indicates that while zinc may not lower the risk of catching a cold, it has shown promise in shortening the duration of existing colds. For instance, a comprehensive analysis highlighted that zinc lozenges could reduce the duration of cold symptoms by up to 8 days in some chronic cases (research ID: 35177991). Moreover, a review of multiple randomized controlled trials suggested a potential average reduction of around 2.25 days for cold symptoms when zinc was utilized alone (research ID: 32342851).
However, it's crucial to note that the effectiveness of zinc appears to vary widely based on individual circumstances, such as the length of the cold at the time of treatment onset (research ID: 35177991). Additionally, while zinc has been included in discussions about over-the-counter treatments for colds, the evidence supporting its isolated effectiveness remains somewhat inconclusive, emphasizing the need for more high-quality research (research ID: 31478634). In conclusion, while zinc may offer some benefits in managing cold symptoms, it should be viewed as a supportive measure rather than a standalone solution for cold prevention or treatment.
Users report various improvements in symptoms related to health and immunity after using zinc picolinate. Many individuals have noted enhanced resilience against common colds and other ailments. For example, one reviewer shared that after starting zinc picolinate, they have not experienced colds over the past three years, highlighting a long-term benefit they attribute to the supplement Read Review. Others mention more immediate relief, indicating that symptoms such as fatigue and malaise improved within days of starting the supplement. A user noted that symptoms diminished significantly after just two days of taking zinc at the first sign of illness Read Review.
Reviews also emphasize additional benefits beyond cold prevention, with users reporting improvements in skin health and hair growth, often mentioning a reduction in skin issues and better hair resilience Read Review. Many users combine zinc with other vitamins and minerals to strengthen their immune system and address deficiencies, which seems to contribute to the overall positive effect on their health and well-being Read Review. However, individual results can vary based on different health conditions, lifestyle factors, and adherence to recommended dosages.
Based on user reviews, many individuals have found that combining zinc picolinate with other vitamins and minerals can enhance its effectiveness in managing common cold symptoms. For instance, one user reported using zinc picolinate alongside other vitamins for 3-7 days when feeling unwell, which helped them avoid the common cold while working in a nursery Read Review. Another review highlighted the effectiveness of combining zinc with vitamin C, particularly as an emergency remedy for the common cold Read Review. Users noted that this combination not only improved their immune response but also contributed positively to their overall health and well-being.
Moreover, many users highlighted the preventive benefits of taking zinc picolinate consistently during cold seasons, with some noting that their families remained healthy throughout the flu season when they collectively used the supplement Read Review. A family using it reported no illness during winter for the first time in years Read Review. These reviews suggest that while zinc is effective on its own, its combined use with other supplements may further bolster immunity and help in effectively combating cold symptoms.
The optimal dose of zinc for treating the common cold isn't definitively established in the existing research, but there are insights about its effect on cold duration. Studies suggest that zinc can potentially reduce the duration of cold symptoms by approximately 2.25 to 4 days, though the effect varies based on the length of the cold when treatment begins. For instance, the Mossad (1996) trial with zinc gluconate lozenges reported an average reduction of around 4.0 days, particularly noting a more significant impact for prolonged colds lasting 15 to 17 days, where it could shorten recovery by up to 8 days [3]. However, zinc's direct efficacy in preventing colds or significantly reducing their incidence remains uncertain [4].
When it comes to supplements, studies have shown that zinc lozenges may improve symptoms for those actively suffering from a cold, but there isn't a universally optimal dosing guideline as research on this topic varies greatly [1]. That said, a clinical review demonstrated that zinc supplementation can shorten cold duration but does not greatly affect the chances of catching a cold [5]. It’s advisable to consult with healthcare professionals for tailored dosing recommendations, especially since individual responses to zinc can vary.
9
Quick recovery
3 people found this helpful
As soon as my husband and I start feeling unwell, we take two tablets of zinc twice a day. After a day or two, the common cold symptoms diminish. It's effective if you act quickly.
9
Prevents onset
2 people found this helpful
At the first sign of a common cold, zinc works wonders. However, I advise against taking it for more than two weeks without analysing your levels.
10
No colds experienced
2 people found this helpful
I've taken one zinc tablet daily from October; it's now February and I haven't had any colds. If I notice any signs of illness, they usually pass the next day, and I believe zinc is responsible for this.
10
Cold prevention
4 people found this helpful
Amazing! I began taking zinc tablets after a bad common cold, and I haven't had one since. This three-year streak is miraculous for me. I find that cuts heal quickly, and I prefer this smaller pill, as it's easier to swallow and absorbs better.
9
Reduced hair loss
61 people found this helpful
After suffering from hair loss and other health issues, I discovered a significant zinc deficiency. Taking zinc picolinate has resolved my hair loss, stabilised my vision, and enhanced my resilience to common colds. I am very satisfied with this product.
9
Skin improvement
9 people found this helpful
Zinc picolinate at 22 mg is well-absorbed as advised by my doctor. I took two tablets daily for two months, then one tablet for maintenance. The small round tablets are easy to swallow and have no side effects. My skin improved with fewer rashes, my hair grew stronger, and my nails became less brittle. It's effective as an emergency remedy for the common cold when combined with vitamin C.
9
Prevents illness
18 people found this helpful
Zinc picolinate from Solgar works wonders. I use it for prevention, and if I feel unwell, I take it for 3-7 days alongside other vitamins. It has helped me avoid the common cold, even while working in a nursery.
9
Supports immune system
2 people found this helpful
This product is very helpful, especially in the cold season. I often start using it at the first sign of a common cold. It supports my body and skin while also being free from GMOs. My family, ranging from 36 to 59, have all seen improvements too.
10
Miraculous immunity
2 people found this helpful
I ordered zinc as a preventative measure against common colds in winter. For the first time in 5 years, I’ve gone through winter without a sore throat or relapse, and I’m thrilled with the results!
9
Zinc shortens cold duration variability
Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration.
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
7
Zinc's unclear role in colds
Potential Role of Vitamins and Zinc on Acute Respiratory Infections Including Covid-19.
We explored the potential effects of zinc on the common cold based on a collection of research studies that investigated its role in treating acute respiratory infections, including COVID-19.
Importantly, we found that while zinc showed some promise in improving conditions related to pneumonia in children under five, there wasn't enough clear evidence linking zinc directly to a reduction in the incidence or duration of the common cold.
Typically, vitamins C, D, and E were examined alongside zinc, with findings indicating that these vitamins did not lower the common cold's occurrence. However, we noted that vitamin C did help shorten its duration and lessen its severity for some individuals, particularly those under physical or environmental stress.
Ultimately, while zinc has been shown to support health in various contexts, its specific impact on the common cold remains uncertain, suggesting that additional research is needed to draw more definitive conclusions.
4
Zinc may shorten cold duration
Zinc for prevention and treatment of the common cold.
We explored how zinc supplementation might impact the prevention and treatment of the common cold. Through a thorough examination of 34 studies involving over 8,500 participants, we aimed to understand whether zinc could effectively reduce the occurrence or duration of colds.
The studies included randomized controlled trials comparing zinc to placebo in both children and adults. Our findings indicate that while zinc may not significantly lower the risk of catching a cold, it could help reduce the duration of an ongoing cold. However, this benefit comes alongside an increase in non-serious side effects, such as an unpleasant taste and stomach issues.
It's important to note that many of these studies showed a wide range of interventions and outcomes, and some reporting was incomplete. Overall, our results suggest that zinc does not hold substantial promise for preventing colds, but it may help shorten the duration of symptoms once a cold strikes.
8
Zinc reduces cold duration
Zinc Supplementation Reduces Common Cold Duration among Healthy Adults: A Systematic Review of Randomized Controlled Trials with Micronutrients Supplementation.
We explored the impact of zinc supplementation on common cold symptoms through an extensive review of 20 randomized controlled trials. These studies focused on observing how micronutrients, especially zinc, can help manage the cold in healthy adults.
Our findings suggest that while zinc did not significantly prevent the incidence of cold or reduce symptom severity when compared to other micronutrients, it showed promising results in potentially shortening the duration of a cold. Specifically, we observed that zinc could cut down the duration of cold symptoms by approximately 2.25 days when used alone.
This reduction in duration could have a meaningful impact on daily life and overall productivity for those affected by the common cold. It's noteworthy that while zinc proves beneficial, other vitamins like vitamin C and vitamin D did not show the same effectiveness in this context.
References
Nault D, Machingo TA, Shipper AG, Antiporta DA, Hamel C, et al. Zinc for prevention and treatment of the common cold. Cochrane Database Syst Rev. 2024;5:CD014914. doi:10.1002/14651858.CD014914.pub2
Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
Hemilä H, Chalker E, Tukiainen J. Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration. Front Pharmacol. 2022;13:817522. doi:10.3389/fphar.2022.817522
Murni IK, Prawirohartono EP, Triasih R. Potential Role of Vitamins and Zinc on Acute Respiratory Infections Including Covid-19. Glob Pediatr Health. 2021;8:2333794X211021739. doi:10.1177/2333794X211021739
Wang MX, Win SS, Pang J. Zinc Supplementation Reduces Common Cold Duration among Healthy Adults: A Systematic Review of Randomized Controlled Trials with Micronutrients Supplementation. Am J Trop Med Hyg. 2020;103:86. doi:10.4269/ajtmh.19-0718
DeGeorge KC, Ring DJ, Dalrymple SN. Treatment of the Common Cold. Am Fam Physician. 2019;100:281.